Production of podophyllotoxin in Linum linearifolium in vitro cultures
نویسندگان
چکیده
منابع مشابه
Effect of Some Phytohormones on Podophyllotoxin Production in Cell and Plantlets Cultures of Linum album
The natural lignan podophyllotoxin, a dimerized product of two phenylpropanoid moieties which occurs in a few plant species, is a pharmacologically important compound for its anticancer activities. Optimization of the in vitro cultures might lead to a renewable source of lignans for medicinal uses. In order to maximize efficiency of podophyllotoxin accumulation via in vitro cultures, the effect...
متن کاملEvaluation of thermal-stress on the accumulation of podophyllotoxin in shoot in vitro cultures of Linum persicum
Linum persicum is an endangered plant native to Iran, from Linaceae family. Phytochemical analysis has shown that L. persicum in vitro cultures contain podophyllotoxin (PTOX), the pharmacological precursor for anticancer drugs such as etoposide, etopophos, and teniposide. Shoot culture of L. persicum was established from callus cultures in MS medium containing GA...
متن کاملCytotoxic activity of in vitro cultures of Linum spp.
There are some reports on the lignan constituents of Linum spp. In this study, we investigated the cyototoxicity of Linum spp. in vitro cultures for the first time. If they show significant cytotoxic activity, they will be valuable candidates for isolation of cytotoxic compounds in large scale from them by tissue culture technology. In our study, we chose normal root, hairy root and calli cultu...
متن کاملCytotoxic activity of in vitro cultures of Linum spp.
There are some reports on the lignan constituents of Linum spp. In this study, we investigated the cyototoxicity of Linum spp. in vitro cultures for the first time. If they show significant cytotoxic activity, they will be valuable candidates for isolation of cytotoxic compounds in large scale from them by tissue culture technology. In our study, we chose normal root, hairy root and calli cultu...
متن کاملeffect of some phytohormones on podophyllotoxin production in cell and plantlets cultures of linum album
the natural lignan podophyllotoxin, a dimerized product of two phenylpropanoid moieties which occurs in a few plant species, is a pharmacologically important compound for its anticancer activities. optimization of the in vitro cultures might lead to a renewable source of lignans for medicinal uses. in order to maximize efficiency of podophyllotoxin accumulation via in vitro cultures, the effect...
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ژورنال
عنوان ژورنال: Pharmacognosy Magazine
سال: 2010
ISSN: 0973-1296
DOI: 10.4103/0973-1296.66932